职称/职务：讲师 政治面貌：群众
·个人简介
赵冠华，硕士生导师，博士毕业于大连工业大学食品科学与工程专业，获工学博士学位。主要从事海洋食品脂质氧化机理、食品成分检测质谱方法、海洋食品精深加工、食品科学生物化学等方面的科研与教学工作。近年来从事食品营养与水产品精深加工方面的研究，主要研究海参、贝类脂质营养成分，开发高附加值海洋功能食品；建立食品加工过程中各种成分检测新方法，提高食品检验检测的准确性，同时，研究加工副产物的高效利用。主持辽宁省科技厅自然基金1项、辽宁省教育厅自主选题项目1项，参加国家重点研发计划“蓝色粮仓科技创新”专项、国家自然科学重点基金、大连市科技创新基金项目重点学科重大课题等项目3项。发表研究论文40余篇，SCI收录28篇。获得大连市高层次“青年才俊”人才称号。担任《Food Research International》、《International Journal of Biological Macromolecules》、《Journal of Food Composition and Analysis》等国外期刊审稿人。目前为美国化学会（ACS）会员、中国食品科学技术学会会员、辽宁省营养学会预制菜与营养专业委员会会员。
·工作经历
2023.10 –至今 大连海洋大学 讲师
·教学及科研项目：
1. 干海参贮藏过程中脂质氧化加速品质劣变的机制及调控研究，辽宁省科技厅，2023.12-2025.11, 主持；
2. 大连海域四种贝类加工贮藏过程中脂质的变化规律及调控研究，辽宁省教育厅，2024.09-2026.09, 主持.
·学术成果
论文（代表论文）：
1. Guan-Hua Zhao, Zi-Xuan Wu, Min Zhang, Ying Luo, Da-Yong Zhou*. A sensitive UHPLC-electrospray tandem mass spectrometry method for the simultaneous quantification of 8 oxysterols and cholesterol in oysters (Crassostrea gigas) with different thermal cooking procedures. Journal of Food Composition and Analysis. 2025,138: 107025.
2. Guan-Hua Zhao, Ying Luo, Qi Li, Min Zhang, Lei Qin, Fa-Wen Yin, Da-Yong Zhou*. Exploring the antioxidant “cut-off effect” of gallic acid alkyl esters in dried oysters (Crassostrea gigas) during storage: an analysis based on oxidation kinetics and molecular dynamics simulations. Food Bioscience. 2023, 56: 103197.
3. Guan-Hua Zhao, Yuan-Yuan Hu, Xiang-Bo Zeng, Min Zhang, Zheng Zhou, Lei Qin, Fa-Wen Yin, Da-Yong Zhou*, Fereidoon Shahidi. A direct and facile simultaneous quantification of non-polar and polar lipids in different species of marine samples using normal-phase HPLC–CAD. Journal of Food Composition and Analysis. 2022, 114: 104813.
4. Guan-Hua Zhao, Yuan-Yuan Hu, Zhong-Yuan Liu, Hong-Kai Xie, Min Zhang, Rui Zheng, Lei Qin, Fa-Wen Yin*, Da-Yong Zhou*. Simultaneous quantification of 24 aldehydes and ketones in oysters (Crassostrea gigas) with different thermal processing procedures by HPLC-electrospray tandem mass spectrometry. Food Research International. 2021,147: 110559.
5. Guan-Hua Zhao, Wen-Fei Zhao, Ling-Shu Han, Jun Ding*, Ya-Qing Chang*. Metabolomics analysis of sea cucumber (Apostichopus japonicus) in different geographical origins using UPLC-Q-TOF/MS. Food Chemistry. 2020, 333: 127453.
6. Guan-Hua Zhao, Xing-Yue Zhai, Min Qu, Chang-Qing Tong, Wei Li*. Sulfated modification of the polysaccharides from Crassostrea gigas and their antioxidant and hepatoprotective activities through metabolomics analysis. International Journal of Biological Macromolecules, 2019, 129:386-395.
7. Guan-Hua Zhao, Xi-Long Hou, Xing-Yao Li, Min Qu, Chang-Qing Tong, Wei Li*. Metabolomics analysis of alloxan-induced diabetes in mice using UPLC–Q-TOF-MS after Crassostrea gigas polysaccharide treatment. International Journal of Biological Macromolecules, 2018, 108:550-557.
8. Yuan-Yuan Hu, Guan-Hua Zhao, Jia-Liang Wang, Zhong-Yuan Liu, Fa-Wen Yin, Lei Qin, Da-Yong Zhou*, Fereidoon Shahidi, Bei-Wei Zhu. Lipid oxidation and aldehyde formation during in vitro gastrointestinal digestion of roasted scallop (Patinopecten yessoensis) - the role of added antioxidant of bamboo leaves. Food & Function. 2021, 12: 11046-11057.
9. Yuan-Yuan Hu, Guan-Hua Zhao, Fa-Wen Yin, Zhong-Yuan Liu, Jia-Liang Wang, Lei Qin, Da-Yong Zhou*, Fereidoon Shahidi, Bei-Wei Zhu. Effects of roasting temperature and time on aldehyde formation derived from lipid oxidation in scallop (Patinopecten yessoensis) and the deterrent effect by antioxidants of bamboo leaves. Food Chemistry, 2022, 369: 130936.
10. Yuan-Yuan Hu, Guan-Hua Zhao, Lei Qin, Zhen-Long Yu, Min Zhang, Xiao-Chi Ma, Da-Yong Zhou*, Fereidoon Shahidi, Bei-Wei Zhu. Trans, trans-2,4-Decadienal induces endothelial cell injury by impairing mitochondrial function and autophagic flux. Food & Function. 2021, 12: 5488-5500.
11. Ying Luo, Guan-Hua Zhao, Xue-Chen Pei, Fa-Wen Yin, Hui-Lin Liu, Lei Qin, Da-Yong Zhou*. The inhibitory effect of gallic acid alkyl esters on lipid oxidation of intactly soaked oyster meats and oyster meat homogenates during refrigerated storage. European Journal of Lipid Science and Technology, 2023, 125: 2200161.
12. 赵冠华, 佟长青, 李伟, 曲敏. 大鲵肽在牙膏中的应用研究. 日用化学工业, 2017, 47(1): 36-39.
13. 赵冠华, 佟长青, 李伟, 曲敏. 硫酸酯化牡蛎多糖对3种肿瘤细胞抑制及凋亡的影响. 食品工业科技, 2017, (13): 302-306.
14. 赵冠华, 佟长青, 李伟, 曲敏. 硫酸酯化牡蛎多糖对四氯化碳所致小鼠急性肝损伤的影响. 大连海洋大学学报, 2018, 33(1): 72-76.
主讲课程
《生物化学》
·研究/招生方向
海洋食品加工贮存过程中脂质氧化研究。